Assist. Prof. Dr. Ismail Hussein Aziz, the assistant dean of the Institute of Genetic Engineering and Biotechnology for Postgraduate Studies at the University of Baghdad, has published a research paper entitled (Study of the pharmacological efficacy of breast cancer treatments Fluorouracil (5FU) and Gemcitabine (GEM) using pharmaceutical metal frames as a Nanocomposite) extracted from a master thesis written by the researcher (Ali Khudhair Rissan) and published in the International Journal of Biological Macromolecules and classified in Scopus database:
The study aimed to develop and improve the therapeutic efficiency of Gemcitabine (GEM) and Fluorouracil (5FU) and to reduce their side effects using mil-100 nanoscale as a carrier. The results of the characterization confirmed the successful composition of the nanocarrier as well as the effect of Hydrogen on the exit of 5FU and GEM of MIL-100, in addition to evaluating the anti-cancer activity of these nanotransmitters through WST-1 analysis by the use of Acridine orange in human breast cancer cells (MCF-7) and control cells (HUVEC). The findings showed that all nanotransmitts have an anti-cancer activity and induced apoptosis in MCF-7 cells, also there is no correlation between ABCA1, body mass index (BMI) and age in breast cancer and the control group.
