Investigation of FOXP3 gene polymorphisms (rs122467173 C/T), new marker in prognosis and diagnostic of type 2 diabetes mullets (T2DM)
Rafid A. Abdul kareem/Al-khwarizimi collage of engineering, biochemical engineering dept., Baghdad University, Iraq
Ali S. Dawood/Department of Pathology and Forensic Medicine, College of Medicine, Wasit University, Wasit, Iraq
Diabetes mellitus is a chronic disease, non-infection, can be occurred in variant ages, also the risk of (DM) increase in advanced ages. Actually the multiple genetic variants and many environmental factors play important roles of (DM).The decreased of insulin produced by pancreas caused by (DM). In present our study we investigated the association of FOXP3 (SNP rs122467173 [C/T]) and type 2 diabetes mellitus. It is worth mentioning, this is unique and first study among the word in this kinds of researches. 120 cases compared with 120 healthy control. Our result approved that an association between FOXP3 and type 2 diabetes mellitus. Also we can consider present result as a new marker, prognosis and diagnostic for occurrence of type 2 diabetes mellitus.