Inventors: Lecturer Dr. Ban H. Adil/Department of Physics, College of Science for Women, University of Baghdad

Prof. Dr. Hamid H. Murbat/Department of Physics, College of Science for Women, University of Baghdad

Assist. Prof. Dr. Mohammed M. Farhan Al-Halbosiy/Biotechnology Research Center, Al-Nahrain University

Abstract

Cold atmospheric pressure plasma was used to treat leishmaniasis in vitro, the L.donovani and L.tropica parasitic are used. For this purpose, the FE-DBD insulating discharge system with a small diameter of 4 mm and the output power of cold plasma was 6.6 watts, which lead to inhibition of growth. The effect of cold atmospheric pressure plasma was also compared with the effect of the drug (pentostam) and also the drug is combined with non-thermal atmospheric pressure plasma with different doses.

The incubation duration was 24 hours after exposure, for the purpose of increasing the effectiveness of treatment, cold plasma doses were 1 minute, 2 minutes and 3 minutes, the doses of pentostam were 2.5 g / ml and 5 g / ml, as well as the mentioned doses is combined (the three cold plasma doses with two doses of pentostam which became 6 doses). The maximum growth inhibition was given combined therapy. These results gave an indication that cold atmospheric plasma has promising future for the treatment of this parasite that threatens people around the world.

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