{"id":19162,"date":"2019-01-28T09:56:07","date_gmt":"2019-01-28T06:56:07","guid":{"rendered":"http:\/\/en.uobaghdad.edu.iq\/?p=19162"},"modified":"2019-01-28T09:56:07","modified_gmt":"2019-01-28T06:56:07","slug":"diagnosing-different-stages-of-breast-cancer-by-using-stag3-gene-as-a-new-biomarker","status":"publish","type":"post","link":"https:\/\/en.uobaghdad.edu.iq\/?p=19162","title":{"rendered":"Diagnosing Different Stages of Breast Cancer by Using STAG3 Gene as a New Biomarker"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p><strong>Inventor: Assist. Prof. Dr. Inam Jassim Lafta\/Joint Pathology Research Unit,\u00a0College of Veterinary Medicine, University of Baghdad<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"color: #3366ff\"><strong>Abstract<\/strong><\/span><\/p>\n<p style=\"text-align: justify\">The studied breast cancer cell lines showed up-regulation of <em>STAG3<\/em> at both the mRNA and protein levels relative to the normal breast tissue using RT-qPCR and immunoblotting, respectively. Additionally, cDNAs from primary breast tumours, representing four different stages of cancer, revealed higher <em>STAG3<\/em> mRNA than normal breast. In which, a tendency for increasing <em>STAG3<\/em> mRNA expression was recorded from stage I through stage IV of breast cancer. Further confirmation of STAG3 protein overexpression was achieved in primary breast tumour tissue sections compared with the normal tissue using IHC. Overall, these data suggest that STAG3 may be a suitable novel biomarker for breast cancer detection.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; Inventor: Assist. Prof. Dr. Inam Jassim Lafta\/Joint Pathology Research Unit,\u00a0College of Veterinary Medicine, University of Baghdad &nbsp; Abstract The &#8230; <\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[6],"tags":[],"class_list":["post-19162","post","type-post","status-publish","format-standard","hentry","category-Patents"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Diagnosing Different Stages of Breast Cancer by Using STAG3 Gene as a New Biomarker - University of Baghdad<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/en.uobaghdad.edu.iq\/?p=19162\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Diagnosing Different Stages of Breast Cancer by Using STAG3 Gene as a New Biomarker - University of Baghdad\" \/>\n<meta property=\"og:description\" content=\"&nbsp; Inventor: Assist. Prof. Dr. Inam Jassim Lafta\/Joint Pathology Research Unit,\u00a0College of Veterinary Medicine, University of Baghdad &nbsp; Abstract The ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/en.uobaghdad.edu.iq\/?p=19162\" \/>\n<meta property=\"og:site_name\" content=\"University of Baghdad\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/uobaghdad.edu.iq\" \/>\n<meta property=\"article:published_time\" content=\"2019-01-28T06:56:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/en.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/2\/2021\/09\/University-of-Baghdad.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"1700\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"English admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/en.uobaghdad.edu.iq\/?p=19162#article\",\"isPartOf\":{\"@id\":\"https:\/\/en.uobaghdad.edu.iq\/?p=19162\"},\"author\":{\"name\":\"English admin\",\"@id\":\"https:\/\/en.uobaghdad.edu.iq\/#\/schema\/person\/2cb5e415b1c0c8f9ce37a1e4f0431361\"},\"headline\":\"Diagnosing Different Stages of Breast Cancer by Using STAG3 Gene as a New Biomarker\",\"datePublished\":\"2019-01-28T06:56:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/en.uobaghdad.edu.iq\/?p=19162\"},\"wordCount\":139,\"publisher\":{\"@id\":\"https:\/\/en.uobaghdad.edu.iq\/#organization\"},\"articleSection\":[\"Patents\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/en.uobaghdad.edu.iq\/?p=19162\",\"url\":\"https:\/\/en.uobaghdad.edu.iq\/?p=19162\",\"name\":\"Diagnosing Different Stages of Breast Cancer by Using STAG3 Gene as a New Biomarker - 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